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Factors Associated with Antiretroviral Therapy Adherence Among a Community-Based Sample of Sexual Minority Older Adults with HIV
This study utilized a stochastic search variable selection (SVSS) approach to explore potential psychosocial and structural factors associated with HIV-related health outcomes among a community-based sample of older sexual minorities (N = 150) in South Florida, an U.S. HIV-epidemic epicenter. After SVSS, a forward entry regression approach suggested unstable housing, illicit substance use, current nicotine use, and depression were all associated with poorer ART adherence among older sexual minority adults living with HIV. No a ssociations between potential correlates and biological measures of HIV disease severity wer...
Source: AIDS and Behavior - September 23, 2023 Category: Infectious Diseases Source Type: research
How Wastewater Testing Can Help Tackle America ’ s Opioid Crisis
Among the many lasting legacies of COVID-19 may be a newfound appreciation for the value of what we flush down the toilet and wash down the drain.
Wastewater can be a rich source of information about infectious diseases, like COVID-19, as well as flu, respiratory syncytial virus (RSV), mpox and polio, since pathogens like viruses are shed in feces, urine and saliva, all of which is drained into sewage treatment plants. Sampling that water is a good way to screen for certain viruses, and, as more people bypass the medical system and labs in favor of testing themselves at home for things like COVID-19, health agencies lik...
Source: TIME: Health - September 21, 2023 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized COVID-19 Source Type: news
Determination and analysis of whole genome sequence of recombinant GII.6P7 norovirus in Ningxia, China
In this study, the detection rate was16.51% (183/1108) in Ningxia from January to December 2020. Among identified genotypes, GII.4[P31] and GII.4[P16] were the dominant genotypes (n = 20 and 18, respectively) while GII.6[P7] was the main type (n = 6) in non-GII.4 strains which was mainly detected in from May to July. The whole genome sequences of the norovirus diarrhea samples identified as GII.6 [P7] with Ct ≤ 30 collected in 2020 were determined. In this study, the complete genome sequences of norovirus strains PL20-044 and QTX20-071 were identified and analyzed phylogenetically. Phylogenetic analysis of the ORF1and OR...
Source: Infection, Genetics and Evolution - September 21, 2023 Category: Genetics & Stem Cells Authors: Qian Chen Jiangtao Ma Lei Gao Ran Xian Kaixin Wei Anqi Shi Fang Yuan Min Cao Yu Zhao Miao Jin Wenhe Kuai Source Type: research
A CRISPR-Cas12a-based platform facilitates the detection and serotyping of Streptococcus suis serotype 2
In this study, we developed a high-fidelity detection and serotyping platform for S. suis serotype 2 based on recombinase polymerase amplification (RPA) and a clustered regularly interspaced short palindromic repeat (CRISPR)-Cas12a system called Cards-SSJ/K. Cards-SSJ had a detection limit of 10 CFU, takes <60 min, and no cross-reaction was found with other S. suis serotypes, closely related Streptococcus spp., or common pig pathogens, and Cards-SSK could differentiate serotype 2 from serotype 1/2. Results from Cards-SSJ and qPCR were equivalent in detecting S. suis serotype 2 in tissue samples. Analysis indicated that ...
Source: Talanta - September 21, 2023 Category: Chemistry Authors: Lu Wang Jing Sun Jiyu Zhao Jieyu Bai Yueling Zhang Yao Zhu Wanjiang Zhang Chunlai Wang Paul R Langford Siguo Liu Gang Li Source Type: research
Revising the roles of aldosterone in vascular physiology and pathophysiology: from electocortin to baxdrostat
Can J Cardiol. 2023 Sep 19:S0828-282X(23)01732-4. doi: 10.1016/j.cjca.2023.08.035. Online ahead of print.ABSTRACTAldosterone was initially identified as a hormone primarily related to regulation of fluid and electrolyte homeostasis. However, over the past twenty years there has been an increasing appreciation of its role in regulation of vascular function and pathophysiology in the setting of hypertension, atherosclerosis, and heart failure. The purpose of this review is to highlight recent advances in our understanding the biology of aldosterone as it relates to the pathophysiology and the management of vascular disease-e...
Source: Atherosclerosis - September 21, 2023 Category: Cardiology Authors: Ross D Feldman Rohan Sanjanwala Raj Padwal Alexander A Leung Source Type: research
Feasibility of a selective targeted strategy of HIV testing in emergency departments: a before-after study
CONCLUSION: Implementation of a strategy to test for HIV in selective clinical situations in the ED is feasible and may lead to a substantial increase in HIV testing and diagnoses.PMID:37729041 | DOI:10.1097/MEJ.0000000000001078
Source: Herpes - September 20, 2023 Category: Infectious Diseases Authors: Juan Gonz ález Del Castillo Em ília Mirò Iria Miguens Patricia Trenc Bego ña Espinosa Lourdes Piedrafita Mar ía Jesús Pérez Elías Santiago Moreno Federico Garc ía Alberto Villamor M íriam Carbó Emili Gen é Òscar Mirò Emergency HIV network in Source Type: research
Necessary to Identify Latent Toxicants A
Dear Editor SARS ‑CoV‑2 is a new coronavirus that emerged in 2019 and caused the COVID‑19 epidemic, but despite much effort, there is still no specific care standard. The lack of accurate information posed several challenges for health systems, which were accompanied by a wide range of possibly unfamiliar mate rials for the treatment and prevention of COVID‑19.[1] When a major medical crisis such as COVID‑19 occurs, and there is no known cure for it, several phenomena may occur, and people to show different behavioral reactions to deal with this condition and treat it with limited knowledge.
Source: International Journal of Preventive Medicine - September 20, 2023 Category: International Medicine & Public Health Source Type: research
Respiratory syncytial virus: can we still believe that after pandemic bronchiolitis is not a critical issue for public health?
Conclusions: The 2022 –2023 bronchiolitis season in Italy started earlier than the usual pre-pandemic seasons but seasonality pattern may be going back to the pre-pandemic one. This season was not more severe than the previous ones. The impact of RSV disease on health care systems and costs remains a critical issue.What is Known:• RSV is one of the major leading causes of hospitalization among children aged less than 3 months. SarsCOV2 pandemic interfered with the seasonal circulation of most respiratory viruses, Including RSV.What is New:• The 2022–2023 bronchiolitis season in Italy started and peaked earlier tha...
Source: European Journal of Pediatrics - September 20, 2023 Category: Pediatrics Source Type: research
A Review of Studies on the Covid-19 Pandemic and the Psychological Effects of Related Measures on Children, Youth and Parents
Turk Psikiyatri Derg. 2023 Fall;34(3):202-214. doi: 10.5080/u25936.ABSTRACTPandemics are social events that affect individuals' lives in many ways and have a significant impact on the mental health of masses. Pandemics and measures taken to combat these epidemics affect children and young people as well as adults. The purpose of the current review is to compile studies that have been conducted on the psychological effects of the COVID-19 pandemic and related measures on children, youth, and parents, and use the findings to shed light on future studies. In this review, 35 studies that were determined as a result of a compre...
Source: Turkish Journal of Psychiatry - September 19, 2023 Category: Psychiatry Authors: Burcu Altin G ülsen Erden Source Type: research
Dietary Supplement Use among Iranian Households during COVID ‑19 Epidemic Lockdown: Less Access in Those Who May Need More National Food and Nutrition Surveillance
Conclusions: During epidemic lockdown, DS use was remarkably increased among the Iranian households. Apart from the debatable usefulness of DSs against COVID‑19, the inverse association of DS use with a household’s income and provincial food security well indicates inequity in accessibility to DS. Actions to improve the nutritional status of the under‑privileged populations including targeted supplementation are strongly recommended.
Source: International Journal of Preventive Medicine - September 19, 2023 Category: International Medicine & Public Health Source Type: research
